Article
Molecular cloning and characterization of a novel isoform of the non-canonical poly(A) polymerase PAPD7.
Biochemical and biophysical research communications - 1 Mar 2013
Ogami Koichi, Cho Rihe, Hoshino Shin-ichi
Abstract excerpt
Non-canonical poly(A) polymerases (ncPAPs) catalyze the addition of poly(A) tail to the 3' end of RNA to play pivotal roles in the regulation of gene expression and also in quality control. Here we identified a novel isoform of the 7th member of ncPAPs: PAPD7 (PAPD7 l), which contains 230 extra amino acids at the amino terminus of the previously identified PAPD7 (PAPD7 s). In sharp contrast to the inactive PAPD7...
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