Article
Novel locus including FGF21 is associated with dietary macronutrient intake.
Human molecular genetics - 1 May 2013
Chu Audrey Y, Workalemahu Tsegaselassie, Paynter Nina P, Rose Lynda M, Giulianini Franco, Tanaka Toshiko, Ngwa Julius S, Qi Qibin, Curhan Gary C, Rimm Eric B, Hunter David J, Pasquale Louis R, Ridker Paul M, Hu Frank B, Chasman Daniel I, Qi Lu
Abstract excerpt
Dietary intake of macronutrients (carbohydrate, protein, and fat) has been associated with risk of chronic conditions such as obesity and diabetes. Family studies have reported a moderate contribution of genetics to variation in macronutrient intake. In a genome-wide meta-analysis of a population-based discovery cohort (n = 33 533), rs838133 in FGF21 (19q13.33), rs197273 near TRAF family member-associated...
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