Article
Evaluation of Combined p57KIP2 Immunohistochemistry and Fluorescent in situ Hybridization Analysis for Hydatidiform Moles Compared with Genotyping Diagnosis.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Sept 2024
Usui Hirokazu, Hoshimoto Kazufusa, Sato Asuka, Kano Motofumi, Fukusato Toshio, Nakatani Yukio, Shozu Makio
Abstract excerpt
Immunostaining with p57KIP2 is a widely used diagnostic technique to differentiate complete hydatidiform moles (CHMs) from partial hydatidiform moles (PHM) and non-molar hydropic abortion. However, distinguishing between PHMs and non-molar hydropic abortions using histopathology alone is often challenging. This study aimed to evaluate the technical validity and additional benefits of using fluorescence in situ...
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