Article
HPA-5 typing discrepancy reveals an Ile503Leu substitution in platelet GPIa (α2 integrin).
Vox sanguinis - 1 Jul 2013
Bertrand G, Jallu V, Beranger T, Bianchi F, Casale C, Dufour V, Chenet C, Quesne J, Martageix C, Kaplan C
Abstract excerpt
BACKGROUND AND OBJECTIVES: In fetal/neonatal thrombocytopenia, maternal alloimmunization is diagnosed by the identification of the maternal alloantibody and the offending paternal antigen inherited by the foetus/neonate. Today, for practical reasons, most laboratories perform platelet genotyping instead of phenotyping. Here, we report the case of a human platelet antigen (HPA)-5 genotype/phenotype discrepancy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.