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Article

FOXM1 Is an Oncogenic Mediator in Ewing Sarcoma

24 Jan 2013

Abstract excerpt

Ewing Family Tumors (Ewing Sarcoma and peripheral Primitive Neuroectodermal Tumor) are common bone and soft tissue malignancies of childhood, adolescence and young adulthood. Chromosomal translocation in these tumors produces fusion oncogenes of the EWS/ETS class, with EWS/FLI1 being by far the most common. EWS/ETS chimera are the only well established driver mutations in these tumors and they function as...

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PMID: 23365673
DOI: 10.1371/journal.pone.0054556

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