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Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

7 Dec 2012

Abstract excerpt

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for personalized cancer medicine. We also highlight resistance mechanisms for epidermal growth factor receptor (EGFR) kinase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23361103
DOI: 10.1038/clpt.2012.237

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