Article
Truncated ERG proteins affect the aggressiveness of prostate cancer.
Medical hypotheses - 1 Apr 2013
Wu Fei, Ding Sentai, Lu Jiaju
Abstract excerpt
Prostate cancer is a significant health problem around the world. It ranks second in newly diagnosed cancers and sixth in leading causes of cancer death among men. More than half of prostate cancer cases have E twenty-six (ETS) gene fusions, which are potential diagnostic markers for prostate cancer. TMPRSS2: ERG gene fusions are the most common types of gene fusions in prostate cancer. However, the association...
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