Article
Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study.
BMC medical genetics - 29 Jan 2013
Dodgen Tyren M, Hochfeld Warren E, Fickl Heidi, Asfaha Sahle M, Durandt Chrisna, Rheeder Paul, Drögemöller Britt I, Wright Galen E B, Warnich Louise, Labuschagne Christiaan D J, van Schalkwyk Antoinette, Gaedigk Andrea, Pepper Michael S
Abstract excerpt
BACKGROUND: Adverse drug reactions and lack of therapeutic efficacy associated with currently prescribed pharmacotherapeutics may be attributed, in part, to inter-individual variability in drug metabolism. Studies on the pharmacogenetics of Cytochrome P450 (CYP) enzymes offer insight into this variability. The objective of this study was to compare the AmpliChip CYP450 Test® (AmpliChip) to alternative genotyping...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.