Article
MDM2 SNP309 promoter polymorphism and p53 mutations in urinary bladder carcinoma stage T1.
BMC urology - 28 Jan 2013
Olsson Hans, Hultman Per, Rosell Johan, Söderkvist Peter, Jahnson Staffan
Abstract excerpt
BACKGROUND: Urinary bladder carcinoma stage T1 is an unpredictable disease that in some cases has a good prognosis with only local or no recurrence, but in others can appear as a more aggressive tumor with progression to more advanced stages. The aim here was to investigate stage T1 tumors regarding MDM2 promoter SNP309 polymorphism, mutations in the p53 gene, and expression of p53 and p16 measured by...
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