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Correlation between melanogenic and catalase activity in in vitro human melanocytes: a synergic strategy against oxidative stress

1 Apr 2008

Abstract excerpt

UV-induced DNA damage can lead to melanoma, the most dangerous form of skin cancer. Understanding the mechanisms employed by melanocytes to protect against UV is therefore a key issue. In melanocytes, catalase is the main enzyme responsible for degrading hydrogen peroxide and we have previously shown that that low basal levels of catalase activity are associated with the light phototype in in vitro and ex vivo...

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PMID: 18426413
DOI: 10.1111/j.1755-148x.2007.00432.x

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