Article
Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).
Gut - 1 Jan 2014
Puthia Manoj, Storm Petter, Nadeem Aftab, Hsiung Sabrina, Svanborg Catharina
Abstract excerpt
BACKGROUND: Most colon cancers start with dysregulated Wnt/β-catenin signalling and remain a major therapeutic challenge. Examining whether HAMLET (human α-lactalbumin made lethal to tumour cells) may be used for colon cancer treatment is logical, based on the properties of the complex and its biological context. OBJECTIVE: To investigate if HAMLET can be used for colon cancer treatment and prevention....
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