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Article

The CXCL12/CXCR4/CXCR7 ligand‐receptor system regulates neuro‐glio‐vascular interactions and vessel growth during human brain development

23 Jan 2013

Abstract excerpt

This study investigates glio-vascular interactions in human fetal brain at midgestation, specifically examining the expression and immunolocalization of the CXCL12/CXCR4/CXCR7 ligand-receptor axis and its possible role in the vascular patterning of the developing brain. At midgestation, the telencephalic vesicles are characterized by well developed radial glia cells (RGCs), the first differentiated astrocytes and...

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PMID: 23344887
DOI: 10.1007/s10545-012-9574-y

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