Article
Early cell lineage specification in a marsupial: a case for diverse mechanisms among mammals.
Development (Cambridge, England) - 1 Mar 2013
Frankenberg Stephen, Shaw Geoff, Freyer Claudia, Pask Andrew J, Renfree Marilyn B
Abstract excerpt
Early cell lineage specification in eutherian mammals results in the formation of a pluripotent inner cell mass (ICM) and trophoblast. By contrast, marsupials have no ICM. Here, we present the first molecular analysis of mechanisms of early cell lineage specification in a marsupial, the tammar wallaby. There was no overt differential localisation of key lineage-specific transcription factors in cleavage and early...
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