Article
[Lynch syndrome and microsatellite instability: a review].
Revue medicale de Liege - 1 Dec 2012
Desselle F, Verset G, Polus M, Louis E, Van Daele D
Abstract excerpt
Microsatellite instability (MSI) phenotype occurs in approximately 15 to 24% of colorectal cancer (CRC) patients and may be sporadic or hereditary. It reflects a mutator phenotype in the tumor due to a lack of mismatch repair system. MSI is indeed one of the characteristics of CRCs occurring in L...
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