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Article

A genotype of modified vaccinia Ankara (MVA) that facilitates replication in suspension cultures in chemically defined medium.

Viruses - 21 Jan 2013

Jordan Ingo, Horn Deborah, John Katrin, Sandig Volker

Abstract excerpt

While vectored vaccines, based on hyperattenuated viruses, may lead to new treatment options against infectious diseases and certain cancers, they are also complex products and sometimes difficult to provide in sufficient amount and purity. To facilitate vaccine programs utilizing host-restricted poxviruses, we established avian suspension cell lines (CR and CR.pIX) and developed a robust, chemically defined,...

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Identifiers

PMID: 23337383
DOI: 10.3390/v5010321
PMCID: PMC3564123

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Source receipt: pubmed, retrieved 7 Sept 2026.

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