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Article

IRGM in autophagy and viral infections

1 Jan 2013

Abstract excerpt

Autophagy is a cell autonomous process allowing each individual cell to fight intracellular pathogens. Autophagy can destroy pathogens within the cytosol, and can elicit innate and adaptive immune responses against microorganisms. Nevertheless, numerous pathogens have developed molecular strategies enabling them to avoid or even exploit autophagy for their own benefit. IRGM (immunity-related GTPase family M) is a...

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PMID: 23335927
DOI: 10.3389/fimmu.2012.00426

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