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TRIM proteins: New players in virus-induced autophagy

1 Feb 2018

Abstract excerpt

Role of autophagy during viral infectionAutophagy is an evolutionarily conserved and intricately regulated cellular process in which damaged or aggregated proteins, organelles, and pathogen-derived components are engulfed by double-membrane structures, termed autophagosomes, and targeted for lysosomal degradation [1].The autophagic process consists of distinct phases that include nucleation, autophagosome...

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PMID: 29389992
DOI: 10.1371/journal.ppat.1006787

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