Article
Segmental copy number loss in the region of Semaphorin 4D gene in patients with acetabular dysplasia.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2013
Sekimoto Tomohisa, Ishii Miho, Emi Mitsuru, Kurogi Syuji, Funamoto Taro, Hamada Hiroaki, Chosa Etsuo
Abstract excerpt
Acetabular dysplasia (AD) appears to be a multi-factorial disease, which may involve both genetic and environmental factors and whose pathogenesis remains obscure. The present study aims to identify a genetic variation that might confer risk of AD. We performed whole-genome screening of a copy number variation (CNV) using a deCODE-Illumina CNV beadchip with 20 female AD patients and 131 control subjects....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.