Article
Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis.
Gastroenterology - 1 Mar 2018
Trépo Eric, Goossens Nicolas, Fujiwara Naoto, Song Won-Min, Colaprico Antonio, Marot Astrid, Spahr Laurent, Demetter Pieter, Sempoux Christine, Im Gene Y, Saldarriaga Joan, Gustot Thierry, Devière Jacques, Thung Swan N, Minsart Charlotte, Sersté Thomas, Bontempi Gianluca, Abdelrahman Karim, Henrion Jean, Degré Delphine, Lucidi Valerio, Rubbia-Brandt Laura, Nair Venugopalan D, Moreno Christophe, Deltenre Pierre, Hoshida Yujin, Franchimont Denis
Abstract excerpt
BACKGROUND & AIMS: Patients with severe alcoholic hepatitis (AH) have a high risk of death within 90 days. Corticosteroids, which can cause severe adverse events, are the only treatment that increases short-term survival. It is a challenge to predict outcomes of patients with severe AH. Therefore, we developed a scoring system to predict patient survival, integrating baseline molecular and clinical variables....
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