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Article

Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene.

Chest - 1 Apr 2013

Kheirandish-Gozal Leila, Khalyfa Abdelnaby, Gozal David, Bhattacharjee Rakesh, Wang Yang

Abstract excerpt

BACKGROUND: Obstructive sleep apnea (OSA) is a highly prevalent disorder that has been associated with an increased risk for cardiovascular morbidity, even in children. However, not all children with OSA manifest alterations in endothelial postocclusive hyperemia, an endothelial nitric oxide synt...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Epigenesis, Genetic

Share to Nitric Oxide Synthase Type III

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 23328840
DOI: 10.1378/chest.12-2026
PMCID: PMC3616686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23328840-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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