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Article

Fine-grained subphenotypes in acute kidney injury populations based on deep clustering: Derivation and interpretation.

International journal of medical informatics - 1 Nov 2024

Tan Yongsen, Huang Jiahui, Zhuang Jinhu, Huang Haofan, Tian Mu, Liu Yong, Wu Ming, Yu Xiaxia

Abstract excerpt

BACKGROUND: Acute kidney injury (AKI) is associated with increased mortality in critically ill patients. Due to differences in the etiology and pathophysiological mechanism, the current AKI criteria put it an embarrassment to evaluate clinical therapy and prognosis. OBJECTIVE: We aimed to identify subphenotypes based on routinely collected clinical data to expose the unique pathophysiologic patterns. METHODS: A...

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PMID: 39068892
DOI: 10.1016/j.ijmedinf.2024.105553

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