Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial prostate cancer: the damage done and lessons learnt.

Nature reviews. Urology - 1 Feb 2013

Taherian Nassim, Hamel Nancy, Bégin Louis R, Bismar Tarek A, Goldgar David E, Feng Bing-Jian, Foulkes William D

Abstract excerpt

BACKGROUND: A 51-year-old French Canadian man presented to his family physician owing to an extensive family history of prostate cancer in five brothers, his father and two paternal uncles. His serum PSA level was 4.9 ng/ml and a six-core biopsy revealed the presence of a prostate adenocarcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Fatal Outcome
Share to ERG gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HOXB13 gene

Share to Homeodomain Proteins

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23318356
DOI: 10.1038/nrurol.2012.257
PMCID: PMC3913476

Genes

BRCA2
BRCA1
ERG
HOXB13

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23318356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial prostate cancer: the damage done and lessons learnt.PMID 23318356Read ↗

Familial prostate cancer: the evidence and the Cancer Research Campaign/British Prostate Group (CRC/BPG) UK Familial Prostate Cancer Study.Semantic proximity Read ↗

High-Grade Prostate Adenocarcinoma in a BRCA2 Germline Mutation Carrier: Precision Oncology and Familial Cascade Testing: a case reportSemantic proximity Read ↗

'Case of the Month' from the National Cancer Institute, Bethesda, MD, USA: investigating genetic aberrations in a patient with high-risk prostate cancer.Semantic proximity Read ↗

New insights into APOBEC-mediated mutagenesis in prostate cancer.Semantic proximity Read ↗

Genetic changes in familial prostate cancer by comparative genomic hybridization.Semantic proximity Read ↗

Hereditary prostate cancer: clinical aspects.Semantic proximity Read ↗

Familial prostate cancer.Semantic proximity Read ↗

Original ArticlesSemantic proximity Read ↗

Inherited NBN Mutations and Prostate Cancer Risk and SurvivalSemantic proximity Read ↗

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study.Semantic proximity Read ↗

Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer.Semantic proximity Read ↗

An inherited NBN mutation is associated with poor prognosis prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.