Article
Genetic evidence for the involvement of NOTCH4 in rheumatoid arthritis and alopecia areata.
Immunology letters - 1 Feb 2013
AlFadhli Suad, Nanda Arti
Abstract excerpt
To explore the genetic association of single nucleotide polymorphisms (SNPs) in the coding region of the NOTCH4, exon 3 C+1297T and exon 5 A+3063G, in a case-control analysis of 58 rheumatoid arthritis (RA) and 98 alopecia areata (AA) and 100 ethnically matched healthy subjects. NOTCH4 polymorphisms were genotyped by standard PCR followed by restriction digestion. Analysis of C+1297T SNP revealed a significant...
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