Article
Gαq gene promoter polymorphisms and rheumatoid arthritis in the Han Chinese population are not associated.
Genetics and molecular research : GMR - 11 Jun 2013
Li Y, Wang Y, He Y, Wang D, Deng L, Du Y, Shi G
Abstract excerpt
Mice that lose Gαq from their immune system can spontaneously develop inflammatory arthritis. Gαq expression in the peripheral blood lymphocytes of rheumatoid arthritis (RA) patients is significantly decreased in comparison to that in healthy individuals, and reduced Gαq expression is closely cor...
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