Article
Lack of association between rare mutations of the SIAE gene and rheumatoid arthritis in a Han Chinese population.
Genetics and molecular research : GMR - 30 Oct 2015
Zhang D D, He F, Liu H T, Hao F, Zhu J
Abstract excerpt
The function of rare genotypes encoding defective variants of sialic acid acetylesterase (SIAE) in some autoimmune diseases, including rheumatoid arthritis (RA), is ambiguous. We determined whether mutations in the SIAE gene are responsible for RA in a Han Chinese population.DNA was prepared from the venous leukocytes of 444 RA patients and 647 normal controls. The coding regions and adjacent intron sequences of...
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