Article
Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid.
Mechanisms of ageing and development - 1 Mar 2013
Frankowski Harald, Alavez Silvestre, Spilman Patricia, Mark Karla A, Nelson Joel D, Mollahan Pamela, Rao Rammohan V, Chen Sylvia F, Lithgow Gordon J, Ellerby H Michael
Abstract excerpt
Lifespan extension through pharmacological intervention may provide valuable tools to understanding the mechanisms of aging and could uncover new therapeutic approaches for the treatment of age-related disease. Although the nematode Caenorhabditis elegans is well known as a particularly suitable model for genetic manipulations, it has been recently used in a number of pharmacological studies searching for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.