Article
Identification and sequencing of a putative variant of proopiomelanocortin in human epidermis and epidermal cells in culture.
The Journal of investigative dermatology - 1 Sept 1998
Can G, Abdel-Malek Z, Porter-Gill P A, Gill P, Boyce S, Grabowski G A, Nordlund J, Farooqui J
Abstract excerpt
Proopiomelanocortin (POMC) is a precursor polypeptide for various bioactive peptides, including adrenocorticotropic hormone, alpha-, beta-, and gamma-melanotropin, beta-endorphin, and beta-lipotropin. Although the classical source of POMC is the pituitary, various studies indicate the expression...
Topics
- Animals
- Base Sequence
- Cattle
- Cells, Cultured
- Epidermal Cells
- Epidermis
- Genetic Variation
- Haplorhini
- Humans
- In Situ Hybridization
- Keratinocytes
- Melanocytes
- Molecular Sequence Data
- Pro-Opiomelanocortin
- RNA Probes
- RNA, Antisense
- Sequence Homology, Nucleic Acid
- Skin Transplantation