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Cardiomyocyte proliferation contributes to heart growth in young humans

9 Jan 2013

Abstract excerpt

The human heart is believed to grow by enlargement but not proliferation of cardiomyocytes (heart muscle cells) during postnatal development. However, recent studies have shown that cardiomyocyte proliferation is a mechanism of cardiac growth and regeneration in animals. Combined with evidence for cardiomyocyte turnover in adult humans, this suggests that cardiomyocyte proliferation may play an unrecognized role...

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PMID: 23302686
DOI: 10.1073/pnas.1214608110

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