Article
IL28B genotype is not useful for predicting treatment outcome in Asian chronic hepatitis B patients treated with pegylated interferon-α.
Journal of gastroenterology and hepatology - 1 May 2013
Holmes Jacinta A, Nguyen Tin, Ratnam Dilip, Heerasing Neel M, Tehan Jane V, Bonanzinga Sara, Dev Anouk, Bell Sally, Pianko Stephen, Chen Robert, Visvanathan Kumar, Hammond Rachel, Iser David, Rusli Ferry, Sievert William, Desmond Paul V, Bowden D Scott, Thompson Alexander J
Abstract excerpt
BACKGROUND AND AIM: IL28B genotype predicts response to pegylated interferon (peg-IFN)-based therapy in chronic hepatitis C. However, the utility of IL28B genotyping in chronic hepatitis B (CHB) cohorts treated with peg-IFN is unclear. It was investigated whether IL28B genotype is associated with peg-IFN treatment outcomes in a predominantly Asian CHB cohort. METHODS: This was a retrospective analysis of CHB...
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