Automated genotyping of biobank samples by multiplex amplification of insertion/deletion polymorphisms.

doi:10.1371/journal.pone.0052750

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Article

Automated genotyping of biobank samples by multiplex amplification of insertion/deletion polymorphisms.

PloS one - 1 Jan 2012

Mathot Lucy, Falk-Sörqvist Elin, Moens Lotte, Allen Marie, Sjöblom Tobias, Nilsson Mats

Abstract excerpt

The genomic revolution in oncology will entail mutational analyses of vast numbers of patient-matched tumor and normal tissue samples. This has meant an increased risk of patient sample mix up due to manual handling. Therefore, scalable genotyping and sample identification procedures are essential to pathology biobanks. We have developed an efficient alternative to traditional genotyping methods suited for...

Topics

Automation, Laboratory
Base Sequence
Colon
Colorectal Neoplasms
DNA
DNA Primers
Female
Fixatives
Formaldehyde
Genome, Human
Genotype
Genotyping Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

INDEL Mutation

Male

Molecular Sequence Data

Paraffin Embedding

Polymerase Chain Reaction

Source

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Identifiers

PMID: 23300761
DOI: 10.1371/journal.pone.0052750
PMCID: PMC3531329

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