Article
JAK2 p.V617F allele burden in myeloproliferative neoplasms one month after allogeneic stem cell transplantation significantly predicts outcome and risk of relapse.
Haematologica - 1 May 2013
Lange Thoralf, Edelmann Anja, Siebolts Udo, Krahl Rainer, Nehring Claudia, Jäkel Nadja, Cross Michael, Maier Jacqueline, Niederwieser Dietger, Wickenhauser Claudia
Abstract excerpt
The risk profile and prognosis of patients with myelofibrosis is well described by the Dynamic International Prognostic Scoring System risk categorization. Allogeneic stem cell transplantation is considered for intermediate-2/high risk disease. However, indicators of prognosis after transplantation are still lacking. Seventy simultaneously collected pairs of trephine and blood samples were quantified for JAK2...
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