Systematic profiling of alternative splicing in Helicobacter pylori-negative gastric cancer and their clinical significance

Abstract excerpt

Abstract Background Alternative splicing (AS) may cause structural and functional variations in the protein to promote the proliferation of tumor cells. However, there is no comprehensive analysis of the clinical significance of AS in Helicobacter pylori-negative gastric cancer (HP− GC). Methods The clinical, gene expression profile data and AS events of 138 HP− GC patients were obtained from the database named...

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