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Article

Xylitol production by NAD(+)-dependent xylitol dehydrogenase (xdhA)- and l-arabitol-4-dehydrogenase (ladA)-disrupted mutants of Aspergillus oryzae.

Journal of bioscience and bioengineering - 1 Apr 2013

Mahmud Asif, Hattori Koji, Hongwen Chen, Kitamoto Noriyuki, Suzuki Tohru, Nakamura Kohei, Takamizawa Kazuhiro

Abstract excerpt

Aspergillus oryzae can metabolize xylan to d-xylose and d-xylose to xylitol. However, accumulation of xylitol is controlled by dehydrogenases, such as xylitol dehydrogenase (XDH) and l-arabitol-4-dehydrogenase (LAD), and fluxed into the pentose phosphate pathway. In A. oryzae, XDH and LAD are encoded by xdhA and ladA, respectively. We disrupted the xdhA and ladA genes individually in an attempt to increase...

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Identifiers

PMID: 23287496
DOI: 10.1016/j.jbiosc.2012.10.017

Genes

XDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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