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Article

Spherical nucleic acid enhanced FO-SPR DNA melting for detection of mutations in Legionella pneumophila.

Analytical chemistry - 5 Feb 2013

Knez Karel, Janssen Kris P F, Spasic Dragana, Declerck Priscilla, Vanysacker Louise, Denis Carla, Tran Dinh T, Lammertyn Jeroen

Abstract excerpt

A home-built fiber optic surface plasmon resonance platform (FO-SPR) was applied to directly screen PCR amplified DNA for mutations. The FO-SPR sensor was used for real-time monitoring of DNA duplex melting during high resolution temperature cycling. The signal of the DNA melting was enhanced by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23286339
DOI: 10.1021/ac303008f

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23286339-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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