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Article

Aerobic fitness does not modify the effect of FTO variation on body composition traits.

PloS one - 1 Jan 2012

Huuskonen Antti, Lappalainen Jani, Oksala Niku, Santtila Matti, Häkkinen Keijo, Kyröläinen Heikki, Atalay Mustafa

Abstract excerpt

PURPOSE: Poor physical fitness and obesity are risk factors for all cause morbidity and mortality. We aimed to clarify whether common genetic variants of key energy intake determinants in leptin (LEP), leptin receptor (LEPR), and fat mass and obesity-associated (FTO) are associated with aerobic and neuromuscular performance, and whether aerobic fitness can alter the effect of these genotypes on body composition....

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23284729
DOI: 10.1371/journal.pone.0051635
PMCID: PMC3524224

Genes

FTO
LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Aerobic fitness does not modify the effect of FTO variation on body composition traits.PMID 23284729Read ↗

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