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Article

Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity.

The Journal of clinical endocrinology and metabolism - 1 Jul 2008

Berentzen T, Kring S I I, Holst C, Zimmermann E, Jess T, Hansen T, Pedersen O, Toubro S, Astrup A, Sørensen T I A

Abstract excerpt

CONTEXT: A common variant in the first intron of FTO (rs9939609, T/A) is associated with fatness in Caucasians. OBJECTIVE: FTO may regulate energy homeostasis through the hypothalamus, and we hypothesized that AA-genotypes of rs9939609 FTO have lower energy expenditure and/or a lower level of phy...

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Source

Identifiers

PMID: 18445669
DOI: 10.1210/jc.2008-0007

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18445669-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity.PMID 18445669Read ↗

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youthSemantic proximity Read ↗

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure.Semantic proximity Read ↗

An obesity-associated FTO gene variant and increased energy intake in children.Semantic proximity Read ↗

FTO variant, energy intake, physical activity and basal metabolic rate in Caucasians. The HAPIEE study.Semantic proximity Read ↗

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.Semantic proximity Read ↗

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.Semantic proximity Read ↗

Impact of the FTO Gene Variation on Appetite and Fat Oxidation in Young Adults.Semantic proximity Read ↗

Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study.Semantic proximity Read ↗

Effect of Obesity-Linked FTO rs9939609 Variant on Physical Activity and Dietary Patterns in Physically Active Men and Women.Semantic proximity Read ↗

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.Semantic proximity Read ↗

Association of the common fat mass and obesity associated (FTO) gene polymorphism with obesity in a Japanese population.Semantic proximity Read ↗

Physical activity attenuates the effect of the FTO genotype on obesity traits in European adults: The Food4Me study.Semantic proximity Read ↗

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