Article
Genetic risk for earlier menarche also influences peripubertal body mass index.
American journal of physical anthropology - 1 Jan 2013
Johnson William, Choh Audrey C, Curran Joanne E, Czerwinski Stefan A, Bellis Claire, Dyer Thomas D, Blangero John, Towne Bradford, Demerath Ellen W
Abstract excerpt
It is unclear whether earlier age at menarche is associated with higher body mass index (BMI) because they share a common genetic underpinning. We investigated the impact of single nucleotide polymorphisms (SNPs) influencing menarche timing on peripubertal BMI. For 556 Fels Longitudinal Study children (277 boys/279 girls) born 1928-1992, a genetic risk score (GRS(42)) was computed as the sum of the number of risk...
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