Article
Non-syndromic thoracic aortic aneurysms and dissections--a genetic review.
Frontiers in bioscience (Landmark edition) - 1 Jan 2013
Zhang Pengyu, Zhang Eryong, Fan Jingxiu, Gu Jun
Abstract excerpt
Thoracic aortic aneurysm and dissections (TAADs) are associated with both high mortality and medical expense. Poor outcomes are preventable by surgical repair; however, identifying individuals at-risk is difficult. Researchers are scanning the human genome to characterize the genetic determinants of TAADs by identifying chromosomal regions, gene mutations, single nucleotide polymorphism (SNP), genomic copy number...
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