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Article

Polyketide synthase gene diversity within the microbiome of the sponge Arenosclera brasiliensis, endemic to the Southern Atlantic Ocean.

Applied and environmental microbiology - 1 Mar 2013

Trindade-Silva Amaro E, Rua Cintia P J, Andrade Bruno G N, Vicente Ana Carolina Paulo, Silva Genivaldo G Z, Berlinck Roberto G S, Thompson Fabiano L

Abstract excerpt

Microbes associated with marine sponges are considered important producers of bioactive, structurally unique polyketides. The synthesis of such secondary metabolites involves type I polyketide synthases (PKSs), which are enzymes that reach a maximum complexity degree in bacteria. The Haplosclerida sponge Arenosclera brasiliensis hosts a complex microbiota and is the source of arenosclerins, alkaloids with...

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PMID: 23275501
DOI: 10.1128/AEM.03354-12
PMCID: PMC3591950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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