Article
Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine sponges.
Applied and environmental microbiology - 1 Apr 2007
Fieseler Lars, Hentschel Ute, Grozdanov Lubomir, Schirmer Andreas, Wen Gaiping, Platzer Matthias, Hrvatin Sinisa, Butzke Daniel, Zimmermann Katrin, Piel Jörn
Abstract excerpt
Numerous marine sponges harbor enormous amounts of as-yet-uncultivated bacteria in their tissues. There is increasing evidence that these symbionts play an important role in the synthesis of protective metabolites, many of which are of great pharmacological interest. In this study, genes for the...
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