Article
Significant associations between GSTM1/GSTT1 polymorphisms and nasopharyngeal cancer risk.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2013
Wei Yumei, Zhou Tao, Lin Haiqun, Sun Mingping, Wang Dongqing, Li Hongsheng, Li Baosheng
Abstract excerpt
Glutathione S-transferases play a critical role in the detoxification and elimination of electrophilic carcinogens by conjugating them to glutathione. Homozygous deletions of GSTM1 and GSTT1 have been suggested as risk factors for some cancers, including colorectal, pancreatic, and esophageal cancers. Results of previous individual studies published to estimate the associations between GSTM1/GSTT1 polymorphisms...
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