Article
Susceptibility of human H3N2 influenza virus to oseltamivir in South Korea, 2009-2011.
Journal of microbiology (Seoul, Korea) - 1 Dec 2012
Park Sehee, Kim Jin Il, Lee Ilseob, Lee Sangmoo, Hwang Min-Woong, Bae Joon-Yong, Heo Jun, Lim Eun-Joo, Seok Won-Seok, Cheong Hee Jin, Song Joon Young, Kim Woo Joo, Park Man-Seong
Abstract excerpt
During the 2009-2011 influenza seasons, 10.26% of the specimens isolated from patients in South Korea were subtyped as H3N2 viruses. Some oseltamivir-sensitive H3N2 samples exhibited different plaque morphologies, and were found to have novel mutations in the neuraminidase gene. In a subsequent analysis using NA mutant viruses, viral compensation against oseltamivir treatment was observed only in the N2 mutant...
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