Article
Heterogeneity of antigen expression in advanced epithelial ovarian cancer.
American journal of obstetrics and gynecology - 1 Apr 1990
Berchuck A, Olt G J, Soisson A P, Kamel A, Soper J T, Boyer C M, Clarke-Pearson D L, Leslie D S, Bast R C
Abstract excerpt
Immunohistochemical techniques were used to evaluate the expression of six antigens (CA 125, TAG 72, CA 19-9, OVTL3, DF3, and transferrin receptor) in frozen sections from the primary tumor and metastases of 20 patients with epithelial ovarian cancer. Heterogeneous expression of most antigens was observed within a given tumor nodule, but in each patient the proportion of cells expressing an antigen was similar in...
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