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[Effect of DNA supercoiling on transcription performed by normal and mutant Escherichia coli RNA-polymerases].

Molekuliarnaia biologiia - 1 Jan 2000

Mirkin S M, Bogdanova E S, Gorlenko AhM, Gragerov A I, Larionov O A

Abstract excerpt

A specific DNA-gyrase, inhibitor, coumermycin A1, causes differential changes in the spectrum of proteins synthesized in E. coli wild types cells, while protein spectrum in the mutant cells with coumermycin-resistant DNA-gyrase is left unaffected. The mutation of RNA-polymerase RpoB265 lowers the sensitivity of bacteria to coumermycin A1, whereas the RpoC3 enhances it. The differences between the normal and...

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PMID: 232746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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