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Association of 5, 10- methylenetetrahydrofolate reductase C677T polymorphism in susceptibility to tropical chronic pancreatitis in north Indian population.

Cellular and molecular biology (Noisy-le-Grand, France) - 22 Dec 2012

Singh S, Choudhuri G, Kumar R, Agarwal S

Abstract excerpt

MTHFR is a key enzyme in folate metabolism that catalyzes the conversion of 5, 10—methlenetetrahydrofolate (5, 10— methylene THF) to 5—methyltetrahydrofolate (5—methyl THF), a predominant circulatory form of folate and methyl donor for the remethylation of homocysteine to methionine. Some studies have shown that C667T polymorphism increases the risk of pancreatic cancer. Since MTHFR is...

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Identifiers

PMID: 23273201

Genes

MTHFR

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