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Article

Monogenic and complex forms of obesity: insights from genetics reveal the leptin-melanocortin signaling pathway as a common player.

Critical reviews in eukaryotic gene expression - 1 Jan 2012

Zegers Doreen, Van Hul Wim, Van Gaal Luc F, Beckers Sigri

Abstract excerpt

The role of genetic factors involved in the etiology of human obesity is beyond question. The identification of the hypothalamic leptin-melanocortin signaling pathway as a critical regulator in energy homeostasis and food intake has been essential for genetic research. In this review, we discuss...

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PMID: 23272802
DOI: 10.1615/critreveukargeneexpr.v22.i4.60

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23272802-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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