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Article

Unraveling the genetics of human obesity.

PLoS genetics - 29 Dec 2006

Mutch David M, Clément Karine

Abstract excerpt

The use of modern molecular biology tools in deciphering the perturbed biochemistry and physiology underlying the obese state has proven invaluable. Identifying the hypothalamic leptin/melanocortin pathway as critical in many cases of monogenic obesity has permitted targeted, hypothesis-driven experiments to be performed, and has implicated new candidates as causative for previously uncharacterized clinical cases...

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Identifiers

PMID: 17196040
DOI: 10.1371/journal.pgen.0020188
PMCID: PMC1756898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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