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Article

RNA Interference Targets Arbovirus Replication in Culicoides Cells

27 Dec 2012

Abstract excerpt

Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms. RNA interference (RNAi) is a sequence-specific RNA degradation mechanism that has been shown to play a major role in the antiviral response against arboviruses in...

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PMID: 23269795
DOI: 10.1128/jvi.02848-12

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