Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-flavivirus analysis reveals sfRNA-independent, 3′ UTR-biased siRNA production from an insect-specific flavivirus

15 Oct 2024

Abstract excerpt

ABSTRACT RNA interference (RNAi) plays an essential role in mosquito antiviral immunity, but it is not known whether viral small interfering RNA (siRNA) profiles differ between mosquito-borne and mosquito-specific viruses. A pan-Orthoflavivirus analysis in Aedes albopictus cells revealed that viral siRNAs were evenly distributed across the viral genome of most representatives of the Flavivirus genus. In contrast,...

Topics

Join the communities discussing this publication.

CRISPR and Genetic Engineering
Invertebrate Immune Response Mechanisms
Mosquito-borne diseases and control

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39404457
DOI: 10.1128/jvi.01215-24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-flavivirus analysis reveals sfRNA-independent, 3′ UTR-biased siRNA production from an insect-specific flavivirusPMID 39404457Read ↗

Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens MosquitoesSemantic proximity Read ↗

Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolutionSemantic proximity Read ↗

Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinant of sfRNA biogenesis and provides new insights into flavivirus evolutionSemantic proximity Read ↗

Small RNA responses of Culex mosquitoes and cell lines during acute and persistent virus infectionSemantic proximity Read ↗

Noncoding Flavivirus RNA Displays RNA Interference Suppressor Activity in Insect and Mammalian CellsSemantic proximity Read ↗

Antiviral RNA Interference Responses Induced by Semliki Forest Virus Infection of Mosquito Cells: Characterization, Origin, and Frequency-Dependent Functions of Virus-Derived Small Interfering RNAsSemantic proximity Read ↗

A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of FlaviviridaeSemantic proximity Read ↗

Flavivirus sfRNA suppresses antiviral RNA interference in cultured cells and mosquitoes and directly interacts with the RNAi machinerySemantic proximity Read ↗

Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAsSemantic proximity Read ↗

Subgenomic Flaviviral RNAs of Dengue VirusesSemantic proximity Read ↗

Determinant host differences in ZIKV sfRNA accumulationSemantic proximity Read ↗

Antiviral RNAi Response in Culex quinquefasciatus-Derived HSU CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.