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Article

Role of the Antiapoptotic Proteins BCL2 and MCL1 in the Neonatal Mouse Ovary1

27 Dec 2012

Abstract excerpt

The mammalian ovarian lifespan is determined at the time of birth through a delicate balance of oocyte survival and apoptosis as primordial follicles form, and the mechanism by which germ cells die is not understood. We hypothesized that two BCL2 family proteins, BCL2 and MCL1, may be responsible for regulating neonatal oocyte survival. Previous work has shown that BCL2 is important for germ cell survival in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23269665
DOI: 10.1095/biolreprod.112.103028

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